Molecular epidemiology and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field isolates in Korea
Identifieur interne : 001A81 ( Main/Exploration ); précédent : 001A80; suivant : 001A82Molecular epidemiology and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field isolates in Korea
Auteurs : Seong-Jun Park [Corée du Sud] ; Dae-Sub Song [Corée du Sud] ; Bong-Kyun Park [Corée du Sud]Source :
- Archives of Virology [ 0304-8608 ] ; 2013-07-01.
Abstract
Abstract: Porcine epidemic diarrhea virus (PEDV) has caused devastating enteric disease in Korean pig farms since its first identification in 1992 in Korea. In the present study, the molecular epidemiology, genetic diversity, and phylogenetic relationship of Korean PEDV field isolates to other reference strains were analyzed using the complete E gene. Genetic analysis showed that each PEDV group had several unique characteristics, which indicated that a specific group PEDVs may be differentiated from another group PEDVs. Phylogenetic analysis showed that recent prevalent Korean PEDV field isolates are closely related to the Chinese field strains and differ genetically from the European strains and the vaccine strains used in Korea, which raises questions of whether a new-type PEDV vaccine may be necessary for preventing PEDV infection more effectively in Korea. Notably, a large deletion identified only in the attenuated DR13 can be utilized as a genetic marker, and the methods developed in this study will help to rapidly detect and differentiate PEDVs.
Url:
DOI: 10.1007/s00705-013-1651-5
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000512
- to stream Istex, to step Curation: 000512
- to stream Istex, to step Checkpoint: 000359
- to stream Main, to step Merge: 001A91
- to stream Main, to step Curation: 001A81
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Molecular epidemiology and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field isolates in Korea</title><author><name sortKey="Park, Seong Jun" sort="Park, Seong Jun" uniqKey="Park S" first="Seong-Jun" last="Park">Seong-Jun Park</name></author><author><name sortKey="Song, Dae Sub" sort="Song, Dae Sub" uniqKey="Song D" first="Dae-Sub" last="Song">Dae-Sub Song</name></author><author><name sortKey="Park, Bong Kyun" sort="Park, Bong Kyun" uniqKey="Park B" first="Bong-Kyun" last="Park">Bong-Kyun Park</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:C8B3335CE47FD1B71B13C7B2DE7CE11675B7A394</idno><date when="2013" year="2013">2013</date><idno type="doi">10.1007/s00705-013-1651-5</idno><idno type="url">https://api.istex.fr/ark:/67375/VQC-2WK3S6NL-T/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000512</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000512</idno><idno type="wicri:Area/Istex/Curation">000512</idno><idno type="wicri:Area/Istex/Checkpoint">000359</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000359</idno><idno type="wicri:doubleKey">0304-8608:2013:Park S:molecular:epidemiology:and</idno><idno type="wicri:Area/Main/Merge">001A91</idno><idno type="wicri:Area/Main/Curation">001A81</idno><idno type="wicri:Area/Main/Exploration">001A81</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Molecular epidemiology and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field isolates in Korea</title><author><name sortKey="Park, Seong Jun" sort="Park, Seong Jun" uniqKey="Park S" first="Seong-Jun" last="Park">Seong-Jun Park</name><affiliation wicri:level="1"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Viral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, 305-806, Daejeon</wicri:regionArea><wicri:noRegion>Daejeon</wicri:noRegion></affiliation><affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Veterinary Medicine Virology Lab, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, 151-742, Gwanak-gu Seoul</wicri:regionArea><orgName type="university">Université nationale de Séoul</orgName><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Song, Dae Sub" sort="Song, Dae Sub" uniqKey="Song D" first="Dae-Sub" last="Song">Dae-Sub Song</name><affiliation wicri:level="1"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Viral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, 305-806, Daejeon</wicri:regionArea><wicri:noRegion>Daejeon</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>University of Science and Technology, 305-350, Daejeon</wicri:regionArea><wicri:noRegion>Daejeon</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Corée du Sud</country></affiliation></author><author><name sortKey="Park, Bong Kyun" sort="Park, Bong Kyun" uniqKey="Park B" first="Bong-Kyun" last="Park">Bong-Kyun Park</name><affiliation wicri:level="4"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Veterinary Medicine Virology Lab, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, 151-742, Gwanak-gu Seoul</wicri:regionArea><orgName type="university">Université nationale de Séoul</orgName><placeName><settlement type="city">Séoul</settlement></placeName></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Corée du Sud</country></affiliation></author></analytic><monogr></monogr><series><title level="j">Archives of Virology</title><title level="j" type="sub">Official Journal of the Virology Division of the International Union of Microbiological Societies</title><title level="j" type="abbrev">Arch Virol</title><idno type="ISSN">0304-8608</idno><idno type="eISSN">1432-8798</idno><imprint><publisher>Springer Vienna</publisher><pubPlace>Vienna</pubPlace><date type="published" when="2013-07-01">2013-07-01</date><biblScope unit="volume">158</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="1533">1533</biblScope><biblScope unit="page" to="1541">1541</biblScope></imprint><idno type="ISSN">0304-8608</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0304-8608</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Porcine epidemic diarrhea virus (PEDV) has caused devastating enteric disease in Korean pig farms since its first identification in 1992 in Korea. In the present study, the molecular epidemiology, genetic diversity, and phylogenetic relationship of Korean PEDV field isolates to other reference strains were analyzed using the complete E gene. Genetic analysis showed that each PEDV group had several unique characteristics, which indicated that a specific group PEDVs may be differentiated from another group PEDVs. Phylogenetic analysis showed that recent prevalent Korean PEDV field isolates are closely related to the Chinese field strains and differ genetically from the European strains and the vaccine strains used in Korea, which raises questions of whether a new-type PEDV vaccine may be necessary for preventing PEDV infection more effectively in Korea. Notably, a large deletion identified only in the attenuated DR13 can be utilized as a genetic marker, and the methods developed in this study will help to rapidly detect and differentiate PEDVs.</div></front></TEI><affiliations><list><country><li>Corée du Sud</li></country><settlement><li>Séoul</li></settlement><orgName><li>Université nationale de Séoul</li></orgName></list><tree><country name="Corée du Sud"><noRegion><name sortKey="Park, Seong Jun" sort="Park, Seong Jun" uniqKey="Park S" first="Seong-Jun" last="Park">Seong-Jun Park</name></noRegion><name sortKey="Park, Bong Kyun" sort="Park, Bong Kyun" uniqKey="Park B" first="Bong-Kyun" last="Park">Bong-Kyun Park</name><name sortKey="Park, Bong Kyun" sort="Park, Bong Kyun" uniqKey="Park B" first="Bong-Kyun" last="Park">Bong-Kyun Park</name><name sortKey="Park, Seong Jun" sort="Park, Seong Jun" uniqKey="Park S" first="Seong-Jun" last="Park">Seong-Jun Park</name><name sortKey="Song, Dae Sub" sort="Song, Dae Sub" uniqKey="Song D" first="Dae-Sub" last="Song">Dae-Sub Song</name><name sortKey="Song, Dae Sub" sort="Song, Dae Sub" uniqKey="Song D" first="Dae-Sub" last="Song">Dae-Sub Song</name><name sortKey="Song, Dae Sub" sort="Song, Dae Sub" uniqKey="Song D" first="Dae-Sub" last="Song">Dae-Sub Song</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001A81 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001A81 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:C8B3335CE47FD1B71B13C7B2DE7CE11675B7A394
|texte= Molecular epidemiology and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field isolates in Korea
}}
| This area was generated with Dilib version V0.6.33. |  |